A young girl developed a life-threatening autoimmune condition called Macrophage Activation Syndrome after a minor rash, requiring chemotherapy treatment.

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Six-year-old Esmae Smith from Southend-on-Sea developed a rash in hot weather and was rushed to Great Ormond Street Hospital on April 16, where she was diagnosed with life-threatening Macrophage Activation Syndrome (MAS), possibly triggered by Systemic Juvenile Idiopathic Arthritis (sJIA), and is now undergoing chemotherapy.

First seen Jun 2, 2026
Last updated Jun 2, 2026
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